|
|
|
|
Product Catalogue
MPI
IDIUM
Scientific Name:
Loperamide HCL
|
|
Composition
Each capsule contains:
Loperamide HCl 2 mg
Properties
Pharmacological studies have shown Loperamide HCl to be a highly potent, long-acting and specific antidiarrhoeal.
Loperamide HCl inhibits propulsive intestinal peristaltis by its direct peripheral effect on the gastro-intestinal wall.
From clinical studies it is evident that Loperamide HCl may be used affectively and safely for the treatment of acute and chronic diarrhoea.
Indications
IDIUM is indicated for the symptomatic control of acute and chronic diarrhoea. In patients with an ileostomy it can be used to reduce the number and volume of stools and to harden their consistency.
Contraindications
IDIUM must not be used:
- In children under 2 years of age
- When inhibition of peristalsis is to be avoided.
- In case of acute ulcerative colitis or pseudomembranous colitis.
- In case of severe hepatic disturbances.
- In case of abdominal distention.
- IDIUM should not be used as the primary therapy in acute dysentery, which is characterized by blood in stools and high fever.
Side Effects
If the dose recommendations and contraindications are respected no major side effects have been observed, apart from few cases of dry mouth and abdominal pain.
Precautions
IDIUM should not be given to infants without medical prescription and supervision. Administration of appropriate fluid and electrolyte replacement therapy is recommended specially in children.
Administration and Dosage
Adults and children over 5 years of age:
- Acute diarrhoea: the initial dose is 2 capsules for adults, and 1 capsule for children;
followed by 1 capsule after any subsequent loose stool.
- Chronic diarrhoea: the initial dose is 2 capsules daily for adults, and 1 capsule daily for
children, the initial dose will be adjusted until 1-2 solid stools a day are obtained which is
usually achieved with a maintenance dose of 1-6 capsules daily.
- The maximum dose for acute and chronic diarrhoea is 8 capsules daily.
Overdosage
In case of overdosage, the following may be observed: Constipation and neurological symptoms (myosis, muscular hypertonia, somnolence and bradypnoea).
If symptoms of Overdosage occur, Naloxone can be given as an anti-dote. Therefore the patient should be monitored closely for at least 48 hours in order to detect a possible depression of the central nervous system
Dosage form
Pack of 20 Capsules
Pack of 400 Capsules
|
|
|
|